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Page 1
Rapid analysis of colipase gene variants by multicapillary electrophoresis.
Jaczó Z, Pál E, Dénes R, Somogyi A, Sasvári-Székely M, Guttman A, Rónai Z. Jaczó Z, et al. Electrophoresis. 2015 Jun;36(11-12):1237-43. doi: 10.1002/elps.201400551. Epub 2015 Mar 12. Electrophoresis. 2015. PMID: 25502231
In this paper, we report a robust and reliable multiplex PCR-RFLP for genotype and haplotype analysis of six SNPs (rs41270082, rs3748051, rs142027015, rs3748048, rs73404011, and rs72925892) of the colipase (CLPS) gene. A multicapillary (12 capillaries) electrophores …
In this paper, we report a robust and reliable multiplex PCR-RFLP for genotype and haplotype analysis of six SNPs (rs41270082, rs3748051, rs …
Assignment of the human pancreatic colipase gene to chromosome 6p21.1 to pter.
Davis RC, Xia YR, Mohandas T, Schotz MC, Lusis AJ. Davis RC, et al. Genomics. 1991 May;10(1):262-5. doi: 10.1016/0888-7543(91)90509-d. Genomics. 1991. PMID: 2045105
Colipase is thought to anchor lipase noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. ...Southern blot analysis of genomic DNA from a panel of mouse-human somatic cell hybrids indicated that the colipase …
Colipase is thought to anchor lipase noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of int …
An epididymis-specific secretory protein Clpsl2 critically regulates sperm motility, acrosomal integrity, and male fertility.
Lu X, Ding F, Lian Z, Chen L, Cao Z, Guan Y, Chen R, Cai D, Yu Y. Lu X, et al. J Cell Biochem. 2018 Jun;119(6):4760-4774. doi: 10.1002/jcb.26668. Epub 2018 Mar 1. J Cell Biochem. 2018. PMID: 29323738
However, the molecular mechanisms that govern these maturational events are still poorly defined. Here we report that Clpsl2, a novel colipase homology, is exclusively expressed in the caupt epididymis and conserved in mammalian. ...And during epididymal transit, the bindi …
However, the molecular mechanisms that govern these maturational events are still poorly defined. Here we report that Clpsl2, a novel col …
Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations.
Lindner I, Helwig U, Rubin D, Li Y, Fisher E, Boeing H, Möhlig M, Spranger J, Pfeiffer A, Hampe J, Schreiber S, Döring F, Schrezenmeir J. Lindner I, et al. Mol Nutr Food Res. 2005 Oct;49(10):972-6. doi: 10.1002/mnfr.200500087. Mol Nutr Food Res. 2005. PMID: 16189801
The protein encoded by the pancreatic colipase (CLPS) gene is an essential cofactor needed by pancreatic triglyceride lipase (PNLIP) for efficient dietary lipid hydrolysis. Since the inhibition of lipase activity was shown to reduce the incidence of type 2 diabetes …
The protein encoded by the pancreatic colipase (CLPS) gene is an essential cofactor needed by pancreatic triglyceride lipase ( …
Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.
Weyrich P, Albet S, Lammers R, Machicao F, Fritsche A, Stefan N, Häring HU. Weyrich P, et al. Exp Clin Endocrinol Diabetes. 2009 Feb;117(2):83-7. doi: 10.1055/s-2008-1078733. Epub 2008 Aug 25. Exp Clin Endocrinol Diabetes. 2009. PMID: 18726866
AIMS: Procolipase (CLPS) is secreted from the exocrine pancreas into the gastrointestinal tract and becomes proteolytically cleaved into colipase and the pentapeptide enterostatin. ...As both high fat diet and obesity contribute to insulin resistance, we investigate …
AIMS: Procolipase (CLPS) is secreted from the exocrine pancreas into the gastrointestinal tract and becomes proteolytically cleaved i …
Time-course microarray analysis for identifying candidate genes involved in obesity-associated pathological changes in the mouse colon.
Bae YJ, Kim SE, Hong SY, Park T, Lee SG, Choi MS, Sung MK. Bae YJ, et al. Genes Nutr. 2016 Nov 22;11:30. doi: 10.1186/s12263-016-0547-x. eCollection 2016. Genes Nutr. 2016. PMID: 27895803 Free PMC article.
Cluster 4, which consisted of genes showing the most significant alterations in expression in response to high-fat diet over 12 weeks, included Apoa4 (apolipoprotein A-IV), Ppap2b (phosphatidic acid phosphatase type 2B), Cel (carboxyl ester lipase), and Clps (colipase …
Cluster 4, which consisted of genes showing the most significant alterations in expression in response to high-fat diet over 12 weeks, inclu …
Decreased postnatal survival and altered body weight regulation in procolipase-deficient mice.
D'Agostino D, Cordle RA, Kullman J, Erlanson-Albertsson C, Muglia LJ, Lowe ME. D'Agostino D, et al. J Biol Chem. 2002 Mar 1;277(9):7170-7. doi: 10.1074/jbc.M108328200. Epub 2001 Dec 20. J Biol Chem. 2002. PMID: 11751900 Free PMC article.
The survivors had fat malabsorption as newborns and as adults, but only when fed a high fat diet. On a low fat diet, the Clps-/- mice did not have steatorrhea. The Clps-/- pups had impaired weight gain and weighed 30% less than Clps+/+ or Clps+/- litte …
The survivors had fat malabsorption as newborns and as adults, but only when fed a high fat diet. On a low fat diet, the Clps-/- mice …
Procolipase gene: no association with early-onset obesity or fat intake.
Wermter AK, Scherag A, Holter K, Reichwald K, Lichtner P, Siegfried W, Blundell J, Lawton C, Whybrow S, Stubbs J, Arch JR, Meitinger T, Platzer M, Hinney A, Hebebrand J. Wermter AK, et al. Obes Facts. 2009;2(1):40-4. doi: 10.1159/000196379. Epub 2009 Feb 9. Obes Facts. 2009. PMID: 20054203 Free PMC article.
BACKGROUND: Several lines of evidence in volvement of procolipase (CLPS) or its derivative enterostatin in dietary fat absorption, regulation of fat intake, and body weight in rodents. We explored the relationship between genetic variation in CLPS, early-onset obesi …
BACKGROUND: Several lines of evidence in volvement of procolipase (CLPS) or its derivative enterostatin in dietary fat absorption, re …
12 results